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Open Access

Peer-reviewed

Research Article

Single Nucleotide Polymorphisms within LIPA (Lysosomal Acid Lipase A) Gene Are Associated with Susceptibility to Premature Coronary Artery Disease. A Replication in the Genetic of Atherosclerotic Disease (GEA) Mexican Study

Gilberto Vargas-Alarcón ,

* E-mail: gvargas63@yahoo.com

Affiliation Department of Molecular Biology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Carlos Posadas-Romero,

Affiliation Department of Endocrinology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Teresa Villarreal-Molina,

Affiliation Cardiovascular Genomics Laboratory, Instituto Nacional de Medicina Genómica (INMEGEN), Mexico City, Mexico
⨯
Edith Alvarez-León,

Affiliation Department of Molecular Biology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Javier Angeles,

Affiliation Department of Molecular Biology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Maite Vallejo,

Affiliation Sociomedical Department, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Rosalinda Posadas-Sánchez,

Affiliation Department of Endocrinology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Guillermo Cardoso,

Affiliation Department of Endocrinology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Aida Medina-Urrutia,

Affiliation Department of Endocrinology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯
Eric Kimura-Hayama

Affiliation Department of Tomography, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
⨯

Single Nucleotide Polymorphisms within LIPA (Lysosomal Acid Lipase A) Gene Are Associated with Susceptibility to Premature Coronary Artery Disease. A Replication in the Genetic of Atherosclerotic Disease (GEA) Mexican Study

Gilberto Vargas-Alarcón,
Carlos Posadas-Romero,
Teresa Villarreal-Molina,
Edith Alvarez-León,
Javier Angeles,
Maite Vallejo,
Rosalinda Posadas-Sánchez,
Guillermo Cardoso,
Aida Medina-Urrutia,
Eric Kimura-Hayama

x

Published: September 17, 2013
https://doi.org/10.1371/journal.pone.0074703

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Coronary heart disease
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Atherosclerosis
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Cardiovascular disease risk
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Cholesterol
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Single nucleotide polymorphisms
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Genome-wide association studies
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Lysosomes
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Mexican people
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