A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors

Xiaoyu Qu; Grace Randhawa; Cynthia Friedman; Brenda F. Kurland; Lena Glaskova; Ilsa Coleman; Elahe Mostaghel; Celestia S. Higano; Christopher Porter; Robert Vessella; Peter S. Nelson; Min Fang

doi:10.1371/journal.pone.0074671

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Peer-reviewed

Research Article

A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors

Xiaoyu Qu,

Affiliation Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Grace Randhawa,

Affiliation Seattle Cancer Care Alliance, Seattle, Washington, United States of America
⨯
Cynthia Friedman,

Affiliation Seattle Cancer Care Alliance, Seattle, Washington, United States of America
⨯
Brenda F. Kurland,

Affiliation Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Lena Glaskova,

Affiliation Seattle Cancer Care Alliance, Seattle, Washington, United States of America
⨯
Ilsa Coleman,

Affiliation Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Elahe Mostaghel,

Affiliations Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, University of Washington, Seattle, Washington, United States of America
⨯
Celestia S. Higano,

Affiliations Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Seattle Cancer Care Alliance, Seattle, Washington, United States of America, University of Washington, Seattle, Washington, United States of America
⨯
Christopher Porter,

Affiliation Virginia Mason Medical Center, Seattle, Washington, United States of America
⨯
Robert Vessella,

Affiliations University of Washington, Seattle, Washington, United States of America, Puget Sound VA Health Care System, Seattle, Washington, United States of America
⨯
Peter S. Nelson,

Affiliations Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, University of Washington, Seattle, Washington, United States of America
⨯
Min Fang

* E-mail: mfang@fhcrc.org

Affiliations Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Seattle Cancer Care Alliance, Seattle, Washington, United States of America, University of Washington, Seattle, Washington, United States of America
⨯

A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors

Xiaoyu Qu,
Grace Randhawa,
Cynthia Friedman,
Brenda F. Kurland,
Lena Glaskova,
Ilsa Coleman,
Elahe Mostaghel,
Celestia S. Higano,
Christopher Porter,
Robert Vessella

Published: September 30, 2013
https://doi.org/10.1371/journal.pone.0074671

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