Aging and Calorie Restriction Oppositely Affect Mitochondrial Biogenesis through TFAM Binding at Both Origins of Mitochondrial DNA Replication in Rat Liver

• Anna Picca,

  Affiliation Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, United States of America

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• Vito Pesce,

  Affiliation Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy

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• Flavio Fracasso,

  Affiliation Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy

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• Anna-Maria Joseph,

  Affiliation Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, United States of America

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• Christiaan Leeuwenburgh,

  Affiliation Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, United States of America

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• Angela M. S. Lezza

  * E-mail: angelamariaserena.lezza@uniba.it

  Affiliation Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy

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