TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity

Go Muto; Hitoshi Kotani; Taisuke Kondo; Rimpei Morita; Sanae Tsuruta; Takashi Kobayashi; Hervé Luche; Hans Joerg Fehling; Matthew Walsh; Yongwon Choi; Akihiko Yoshimura

doi:10.1371/journal.pone.0074639

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Open Access

Peer-reviewed

Research Article

TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity

Go Muto ,

Contributed equally to this work with: Go Muto, Hitoshi Kotani, Taisuke Kondo

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯
Hitoshi Kotani ,

Contributed equally to this work with: Go Muto, Hitoshi Kotani, Taisuke Kondo

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯
Taisuke Kondo ,

Contributed equally to this work with: Go Muto, Hitoshi Kotani, Taisuke Kondo

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯
Rimpei Morita,

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯
Sanae Tsuruta,

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯
Takashi Kobayashi,

Affiliations Japan Science and Technology Agency (JST), CREST, Tokyo, Japan, Department of Infectious Disease Control, Faculty of Medicine, Oita University, Idaigaoka, Hasama, Yufu-shi, Oita, Japan
⨯
Hervé Luche,

Affiliation Institute of Immunology, University Clinics, Ulm, Ulm, Germany
⨯
Hans Joerg Fehling,

Affiliation Institute of Immunology, University Clinics, Ulm, Ulm, Germany
⨯
Matthew Walsh,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Yongwon Choi,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Akihiko Yoshimura

* E-mail: yoshimura@a6.keio.jp

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯

TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity

Go Muto,
Hitoshi Kotani,
Taisuke Kondo,
Rimpei Morita,
Sanae Tsuruta,
Takashi Kobayashi,
Hervé Luche,
Hans Joerg Fehling,
Matthew Walsh,
Yongwon Choi

Published: September 13, 2013
https://doi.org/10.1371/journal.pone.0074639

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