BAD Dephosphorylation and Decreased Expression of MCL-1 Induce Rapid Apoptosis in Prostate Cancer Cells

Dana Yancey; Kyle C. Nelson; Daniele Baiz; Sazzad Hassan; Anabel Flores; Ashok Pullikuth; Yelena Karpova; Linara Axanova; Victoria Moore; Guangchao Sui; George Kulik

doi:10.1371/journal.pone.0074561

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Open Access

Peer-reviewed

Research Article

BAD Dephosphorylation and Decreased Expression of MCL-1 Induce Rapid Apoptosis in Prostate Cancer Cells

Dana Yancey ,

Contributed equally to this work with: Dana Yancey, Kyle C. Nelson

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Kyle C. Nelson ,

Contributed equally to this work with: Dana Yancey, Kyle C. Nelson

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Daniele Baiz,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Sazzad Hassan,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Anabel Flores,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Ashok Pullikuth,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Yelena Karpova,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Linara Axanova,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
Victoria Moore,

Affiliation Department of Chemistry, Elon University, Elon, North Carolina, United States of America
⨯
Guangchao Sui,

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯
George Kulik

* E-mail: gkulik@wakehealth.edu

Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America
⨯

BAD Dephosphorylation and Decreased Expression of MCL-1 Induce Rapid Apoptosis in Prostate Cancer Cells

Dana Yancey,
Kyle C. Nelson,
Daniele Baiz,
Sazzad Hassan,
Anabel Flores,
Ashok Pullikuth,
Yelena Karpova,
Linara Axanova,
Victoria Moore,
Guangchao Sui

Published: September 5, 2013
https://doi.org/10.1371/journal.pone.0074561

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Apoptosis
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Prostate cancer
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Cancer treatment
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Transfection
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DU145 cells
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Phosphorylation
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Outer membrane proteins
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Prostate gland
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