Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction

Fuli Zhu; Yulin Li; Junmeng Zhang; Chunmei Piao; Tingting Liu; Hui-Hua Li; Jie Du

doi:10.1371/journal.pone.0074535

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Open Access

Peer-reviewed

Research Article

Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction

Fuli Zhu,

Affiliation Beijing AnZhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, the Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing, China
⨯
Yulin Li,

Affiliation Beijing AnZhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, the Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing, China
⨯
Junmeng Zhang,

Affiliation Beijing AnZhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, the Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing, China
⨯
Chunmei Piao,

Affiliation Beijing AnZhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, the Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing, China
⨯
Tingting Liu,

Affiliation Beijing AnZhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, the Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing, China
⨯
Hui-Hua Li,

Affiliation Department of Physiology and Pathophysiology, Capital Medical University, Beijing, China
⨯
Jie Du

* E-mail: jdu@bcm.edu

Affiliation Beijing AnZhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, the Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing, China
⨯

Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction

Fuli Zhu,
Yulin Li,
Junmeng Zhang,
Chunmei Piao,
Tingting Liu,
Hui-Hua Li,
Jie Du

Published: September 11, 2013
https://doi.org/10.1371/journal.pone.0074535

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Fibroblasts
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Heart
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Hypoxia
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Myocardial infarction
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Collagens
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Fibrosis
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Cell staining
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Senescence
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