Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

Raj Vuppalanchi; Tiebing Liang; Chirayu Pankaj Goswami; Rohit Nalamasu; Lang Li; David Jones; Rongrong Wei; Wanqing Liu; Vishal Sarasani; Sarath Chandra Janga; Naga Chalasani

doi:10.1371/journal.pone.0074471

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Open Access

Peer-reviewed

Research Article

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

Raj Vuppalanchi ,

Contributed equally to this work with: Raj Vuppalanchi, Tiebing Liang

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Tiebing Liang ,

Contributed equally to this work with: Raj Vuppalanchi, Tiebing Liang

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Chirayu Pankaj Goswami,

Affiliation Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Rohit Nalamasu,

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Lang Li,

Affiliation Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
David Jones,

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Rongrong Wei,

Affiliation Department of Medicinal Chemistry & Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, United States of America
⨯
Wanqing Liu,

Affiliation Department of Medicinal Chemistry & Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, United States of America
⨯
Vishal Sarasani,

Affiliation Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Sarath Chandra Janga,

Affiliation Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Naga Chalasani

* E-mail: nchalasa@iu.edu

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

Raj Vuppalanchi,
Tiebing Liang,
Chirayu Pankaj Goswami,
Rohit Nalamasu,
Lang Li,
David Jones,
Rongrong Wei,
Wanqing Liu,
Vishal Sarasani,
Sarath Chandra Janga

Published: September 13, 2013
https://doi.org/10.1371/journal.pone.0074471

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MicroRNAs
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Cirrhosis
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Gene expression
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Messenger RNA
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Microarrays
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Protein expression
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Liver diseases
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Untranslated regions
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