Inhibition of RUNX2 Transcriptional Activity Blocks the Proliferation, Migration and Invasion of Epithelial Ovarian Carcinoma Cells

Zhi-Qiang Wang; Mamadou Keita; Magdalena Bachvarova; Stephane Gobeil; Chantale Morin; Marie Plante; Jean Gregoire; Marie-Claude Renaud; Alexandra Sebastianelli; Xuan Bich Trinh; Dimcho Bachvarov

doi:10.1371/journal.pone.0074384

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Open Access

Peer-reviewed

Research Article

Inhibition of RUNX2 Transcriptional Activity Blocks the Proliferation, Migration and Invasion of Epithelial Ovarian Carcinoma Cells

Zhi-Qiang Wang ,

Contributed equally to this work with: Zhi-Qiang Wang, Mamadou Keita

Affiliations Department of Molecular Medicine, Laval University, Québec (Québec), Canada, Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada
⨯
Mamadou Keita ,

Contributed equally to this work with: Zhi-Qiang Wang, Mamadou Keita

Affiliations Department of Molecular Medicine, Laval University, Québec (Québec), Canada, Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada
⨯
Magdalena Bachvarova,

Affiliation Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada
⨯
Stephane Gobeil,

Affiliations Department of Molecular Medicine, Laval University, Québec (Québec), Canada, Centre de recherche du CHU de Québec, CHUL, Québec (Québec), Canada
⨯
Chantale Morin,

Affiliation Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada
⨯
Marie Plante,

Affiliations Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada, Department of Obstetrics and Gynecology, Laval University, Québec (Québec), Canada
⨯
Jean Gregoire,

Affiliations Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada, Department of Obstetrics and Gynecology, Laval University, Québec (Québec), Canada
⨯
Marie-Claude Renaud,

Affiliations Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada, Department of Obstetrics and Gynecology, Laval University, Québec (Québec), Canada
⨯
Alexandra Sebastianelli,

Affiliations Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada, Department of Obstetrics and Gynecology, Laval University, Québec (Québec), Canada
⨯
Xuan Bich Trinh,

Affiliations Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada, Department of Gynecological Oncology, Antwerp University Hospital, Antwerp, Belgium
⨯
Dimcho Bachvarov

* E-mail: dimtcho.batchvarov@crhdq.ulaval.ca

Affiliations Department of Molecular Medicine, Laval University, Québec (Québec), Canada, Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec (Québec), Canada
⨯

Inhibition of RUNX2 Transcriptional Activity Blocks the Proliferation, Migration and Invasion of Epithelial Ovarian Carcinoma Cells

Zhi-Qiang Wang,
Mamadou Keita,
Magdalena Bachvarova,
Stephane Gobeil,
Chantale Morin,
Marie Plante,
Jean Gregoire,
Marie-Claude Renaud,
Alexandra Sebastianelli,
Xuan Bich Trinh

Published: October 4, 2013
https://doi.org/10.1371/journal.pone.0074384

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DNA methylation
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Ovarian cancer
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