Allosteric Coupling between the Intracellular Coupling Helix 4 and Regulatory Sites of the First Nucleotide-binding Domain of CFTR

Open Access

Peer-reviewed

Research Article

Jennifer E. Dawson,

Affiliations Molecular Structure and Function Program, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
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Patrick J. Farber,

Affiliations Molecular Structure and Function Program, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
⨯
Julie D. Forman-Kay

* E-mail: forman@sickkids.ca

Affiliations Molecular Structure and Function Program, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
⨯

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Allosteric regulation
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Solubility
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Ion channel gating
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NMR spectroscopy
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Chemical elements
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Nucleotides
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Binding analysis
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Deletion mutation
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