Deletion of Hepatic FoxO1/3/4 Genes in Mice Significantly Impacts on Glucose Metabolism through Downregulation of Gluconeogenesis and Upregulation of Glycolysis

Open Access

Peer-reviewed

Research Article

Xiwen Xiong,

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Rongya Tao,

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Ronald A. DePinho,

Affiliation Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
X. Charlie Dong

* E-mail: xcdong@iu.edu

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Glucose metabolism
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Genetically modified animals
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Mouse models
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Glucose tolerance tests
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Insulin
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Diet
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Blood sugar
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Gene expression
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