A Polymorphism at Position 400 in the Connection Subdomain of HIV-1 Reverse Transcriptase Affects Sensitivity to NNRTIs and RNaseH Activity

• David W. Wright ,

  Contributed equally to this work with: David W. Wright, Ilona P. Deuzing

  Affiliation Centre for Computational Science, Department of Chemistry, University College London, United Kingdom

  ⨯
• Ilona P. Deuzing ,

  Contributed equally to this work with: David W. Wright, Ilona P. Deuzing

  Affiliation Department of Virology, ViroscienceLab, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Philippe Flandre,

  Affiliation Institut National de la Santé et de la Recherche Médicale UMR-S 943 and Université Pierre and Marie Curie, Paris, France

  ⨯
• Peter van den Eede,

  Affiliation Janssen Diagnostics BVBA, Beerse, Belgium

  ⨯
• Micheline Govaert,

  Affiliation Janssen Diagnostics BVBA, Beerse, Belgium

  ⨯
• Laurentia Setiawan,

  Current address: Laboratory of Viral Immune Pathogenesis, Department of Experimental Immunology, Academic Medical Centre, Amsterdam, the Netherlands

  Affiliation Department of Virology, ViroscienceLab, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Peter V. Coveney,

  Affiliation Centre for Computational Science, Department of Chemistry, University College London, United Kingdom

  ⨯
• Anne-Geneviève Marcelin,

  Affiliation Institut National de la Santé et de la Recherche Médicale UMR-S 943 and Université Pierre and Marie Curie, Paris, France

  ⨯
• Vincent Calvez,

  Affiliation Institut National de la Santé et de la Recherche Médicale UMR-S 943 and Université Pierre and Marie Curie, Paris, France

  ⨯
• Charles A. B. Boucher,

  Affiliation Department of Virology, ViroscienceLab, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Nancy Beerens

  * E-mail: n.beerens@erasmusmc.nl

  Affiliation Department of Virology, ViroscienceLab, Erasmus MC, Rotterdam, The Netherlands

  ⨯