Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice

Patrick Brennecke; Matthias J. E. Arlt; Roman Muff; Carmen Campanile; Ana Gvozdenovic; Knut Husmann; Nathalie Holzwarth; Elisabetta Cameroni; Felix Ehrensperger; Marcus Thelen; Walter Born; Bruno Fuchs

doi:10.1371/journal.pone.0074045

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Open Access

Peer-reviewed

Research Article

Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice

Patrick Brennecke,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Matthias J. E. Arlt,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Roman Muff,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Carmen Campanile,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Ana Gvozdenovic,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Knut Husmann,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Nathalie Holzwarth,

Affiliation Institute of Veterinary Pathology, Division of Immunopathology, University Zurich, Switzerland
⨯
Elisabetta Cameroni,

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
⨯
Felix Ehrensperger,

Affiliation Institute of Veterinary Pathology, Division of Immunopathology, University Zurich, Switzerland
⨯
Marcus Thelen,

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
⨯
Walter Born,

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯
Bruno Fuchs

* E-mail: bfuchs@research.balgrist.ch

Affiliation Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zürich, Switzerland
⨯

Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice

Patrick Brennecke,
Matthias J. E. Arlt,
Roman Muff,
Carmen Campanile,
Ana Gvozdenovic,
Knut Husmann,
Nathalie Holzwarth,
Elisabetta Cameroni,
Felix Ehrensperger,
Marcus Thelen

Published: September 10, 2013
https://doi.org/10.1371/journal.pone.0074045

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