Methylated DNA Binding Domain Protein 2 (MBD2) Coordinately Silences Gene Expression through Activation of the MicroRNA hsa-mir-496 Promoter in Breast Cancer Cell Line

Open Access

Peer-reviewed

Research Article

Sebastian Alvarado,

Affiliation Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
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Joanne Wyglinski,

Affiliation Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
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Matthew Suderman,

Affiliations Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada, McGill Centre for Bioinformatics, McGill University, Montreal, Quebec, Canada
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Stephen A. Andrews,

Affiliation Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
⨯
Moshe Szyf

* E-mail: moshe.szyf@mcgill.ca

Affiliations Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada, Sackler Program for Epigenetics and Developmental Psychobiology, McGill University, Montreal, Quebec, Canada
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DNA methylation
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MicroRNAs
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Gene expression
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Breast cancer
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Gene regulation
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Transfection
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DNA-binding proteins
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DNA
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