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Open Access

Peer-reviewed

Research Article

Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus

Elisa Callegari,

Affiliation Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy
⨯
Bahaeldin K. Elamin,

Affiliations Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy, Department of Microbiology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan
⨯
Lucilla D’Abundo,

Affiliation Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy
⨯
Simonetta Falzoni,

Affiliation Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy
⨯
Giovanna Donvito,

Affiliation Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy
⨯
Farzaneh Moshiri,

Affiliations Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy, Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
⨯
Maddalena Milazzo,

Affiliation Centro di Ricerca Biomedica Applicata e Dipartimento di Medicina Interna, Policlinico S. Orsola-Malpighi e Università di Bologna, Bologna, Italy
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Giuseppe Altavilla,

Affiliation Dipartimento di Scienze Medico Diagnostiche e Terapie Speciali, Università di Padova, Padova, Italy
⨯
Luciano Giacomelli,

Affiliation Dipartimento di Scienze Medico Diagnostiche e Terapie Speciali, Università di Padova, Padova, Italy
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Francesca Fornari,

Affiliation Centro di Ricerca Biomedica Applicata e Dipartimento di Medicina Interna, Policlinico S. Orsola-Malpighi e Università di Bologna, Bologna, Italy
⨯
Akseli Hemminki,

Affiliation Cancer Gene Therapy Group, Molecular Cancer Biology Program & Transplantation Laboratory & Haartman Institute, University of Helsinki, Helsinki, Finland
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Francesco Di Virgilio,

Affiliation Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy
⨯
Laura Gramantieri,

Affiliation Centro di Ricerca Biomedica Applicata e Dipartimento di Medicina Interna, Policlinico S. Orsola-Malpighi e Università di Bologna, Bologna, Italy
⨯
Massimo Negrini ,

* E-mail: sbs@unife.it (SS); ngm@unife.it (MN)

Affiliation Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italy
⨯
Silvia Sabbioni

* E-mail: sbs@unife.it (SS); ngm@unife.it (MN)

Affiliation Dipartimento di Scienze della Vita e Biotecnologie, Università di Ferrara, Ferrara, Italy
⨯

Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus

Elisa Callegari,
Bahaeldin K. Elamin,
Lucilla D’Abundo,
Simonetta Falzoni,
Giovanna Donvito,
Farzaneh Moshiri,
Maddalena Milazzo,
Giuseppe Altavilla,
Luciano Giacomelli,
Francesca Fornari

x

Published: September 12, 2013
https://doi.org/10.1371/journal.pone.0073964

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Hepatocellular carcinoma
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Viral replication
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Adenoviruses
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Cancer treatment
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Polymerase chain reaction
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MicroRNAs
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Mouse models
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Oncolytic viruses
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