Overexpression of Arginine Transporter CAT-1 Is Associated with Accumulation of L-Arginine and Cell Growth in Human Colorectal Cancer Tissue

Ying Lu; Weimin Wang; Junchen Wang; Chunzhang Yang; Huiming Mao; Xuelian Fu; Yanling Wu; Jingping Cai; Junyi Han; Zengguang Xu; Zhengping Zhuang; Zhongmin Liu; Hai Hu; Bingguan Chen

doi:10.1371/journal.pone.0073866

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Open Access

Peer-reviewed

Research Article

Overexpression of Arginine Transporter CAT-1 Is Associated with Accumulation of L-Arginine and Cell Growth in Human Colorectal Cancer Tissue

Ying Lu ,

Contributed equally to this work with: Ying Lu, Weimin Wang

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Weimin Wang ,

Contributed equally to this work with: Ying Lu, Weimin Wang

Affiliation Department of Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, PR China
⨯
Junchen Wang,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Chunzhang Yang,

Affiliation Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Huiming Mao,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Xuelian Fu,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Yanling Wu,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Jingping Cai,

Affiliation Department of Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, PR China
⨯
Junyi Han,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Zengguang Xu,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Zhengping Zhuang,

Affiliation Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Zhongmin Liu,

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Hai Hu ,

* E-mail: huhailc@sina.com (HH); chen.bingguan@seimc.com.cn (BC)

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Bingguan Chen

* E-mail: huhailc@sina.com (HH); chen.bingguan@seimc.com.cn (BC)

Affiliation Clinical Translational Medical Research Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯

Overexpression of Arginine Transporter CAT-1 Is Associated with Accumulation of L-Arginine and Cell Growth in Human Colorectal Cancer Tissue

Ying Lu,
Weimin Wang,
Junchen Wang,
Chunzhang Yang,
Huiming Mao,
Xuelian Fu,
Yanling Wu,
Jingping Cai,
Junyi Han,
Zengguang Xu

Published: September 6, 2013
https://doi.org/10.1371/journal.pone.0073866

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