Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and Death

Open Access

Peer-reviewed

Research Article

Bianka Mussil,

Affiliation Molecular Retrovirology Unit, Institut Pasteur, Paris, France
⨯
Rodolphe Suspène,

Affiliation Molecular Retrovirology Unit, Institut Pasteur, Paris, France
⨯
Marie-Ming Aynaud,

Affiliation Molecular Retrovirology Unit, Institut Pasteur, Paris, France
⨯
Anne Gauvrit,

Affiliation Molecular Retrovirology Unit, Institut Pasteur, Paris, France
⨯
Jean-Pierre Vartanian,

Affiliation Molecular Retrovirology Unit, Institut Pasteur, Paris, France
⨯
Simon Wain-Hobson

* E-mail: simon.wain-hobson@pasteur.fr

Affiliation Molecular Retrovirology Unit, Institut Pasteur, Paris, France
⨯

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Transfection
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Apoptosis
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HeLa cells
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T cells
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DNA damage
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Cell cycle and cell division
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Flow cytometry
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Mammalian genomics
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