Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth

Mayumi Tomita; Misako Asada; Nariaki Asada; Jin Nakamura; Akiko Oguchi; Atsuko Y. Higashi; Shuichiro Endo; Elizabeth Robertson; Takeshi Kimura; Toru Kita; Aris N. Economides; Jordan Kreidberg; Motoko Yanagita

doi:10.1371/journal.pone.0073554

Loading metrics

Open Access

Peer-reviewed

Research Article

Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth

Mayumi Tomita,

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Misako Asada,

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Nariaki Asada,

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Jin Nakamura,

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Akiko Oguchi,

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Atsuko Y. Higashi,

Affiliation Department of Pharmacology, Kansai Medical University, Moriguchi-city, Osaka, Japan
⨯
Shuichiro Endo,

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Elizabeth Robertson,

Affiliation Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
⨯
Takeshi Kimura,

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯
Toru Kita,

Affiliation Kobe City Medical Center General Hospital, Kobe-city, Hyogo, Japan
⨯
Aris N. Economides,

Affiliation Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
⨯
Jordan Kreidberg,

Affiliation Children’s Hospital Boston, Harvard Medical School, Boston, Massachusettes, United States of America
⨯
Motoko Yanagita

* E-mail: motoy@kuhp.kyoto-u.ac.jp

Affiliation Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto-city, Kyoto, Japan
⨯

Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth

Mayumi Tomita,
Misako Asada,
Nariaki Asada,
Jin Nakamura,
Akiko Oguchi,
Atsuko Y. Higashi,
Shuichiro Endo,
Elizabeth Robertson,
Takeshi Kimura,
Toru Kita

Published: August 26, 2013
https://doi.org/10.1371/journal.pone.0073554

Reader Comments (2)

Post a new comment on this article

1 Response

21 Sep 2013
10:19 GMT
Most Recent

Intepretation of results seems backwards Posted by molecularman71 on 09 Sep 2013 at 17:03 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Kidneys
Is the Subject Area "Kidneys" applicable to this article?

Thanks for your feedback.
Glomeruli
Is the Subject Area "Glomeruli" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Nephrons
Is the Subject Area "Nephrons" applicable to this article?

Thanks for your feedback.
Stem cells
Is the Subject Area "Stem cells" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.