The HDAC Inhibitor LBH589 Induces ERK-Dependent Prometaphase Arrest in Prostate Cancer via HDAC6 Inactivation and Down-Regulation

• Mei-Jen Chuang,

  Affiliation Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

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• Sheng-Tang Wu,

  Affiliation Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

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• Shou-Hung Tang,

  Affiliation Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

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• Xiang-Me Lai,

  Affiliation Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, ROC

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• Hsiao-Chu Lai,

  Affiliation Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, ROC

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• Kai-Hsiang Hsu,

  Affiliation Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, ROC

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• Kuang-Hui Sun,

  Affiliation Department of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan, ROC

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• Guang-Huan Sun,

  Affiliation Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

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• Sun-Yran Chang,

  Affiliations Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC, Taipei City Hospital, Taipei, Taiwan, ROC

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• Dah-Shyong Yu,

  Affiliation Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

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• Pei-Wen Hsiao,

  Affiliation Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan, ROC

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• Shih-Ming Huang,

  Affiliation Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan, ROC

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• Tai-Lung Cha

  * E-mail: tlcha@ndmctsgh.edu.tw

  Affiliations Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC, Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan, ROC, Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, ROC, Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, ROC

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