Prednisolone as Preservation Additive Prevents from Ischemia Reperfusion Injury in a Rat Model of Orthotopic Lung Transplantation

Patrick Paulus; Johannes Holfeld; Anja Urbschat; Haitham Mutlak; Pia Alexandra Ockelmann; Sabine Tacke; Kai Zacharowski; Christin Reissig; David Stay; Bertram Scheller

doi:10.1371/journal.pone.0073298

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Peer-reviewed

Research Article

Prednisolone as Preservation Additive Prevents from Ischemia Reperfusion Injury in a Rat Model of Orthotopic Lung Transplantation

Patrick Paulus ,

* E-mail: Patrick.Paulus@kgu.de

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Johannes Holfeld,

Affiliation Clinic of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria
⨯
Anja Urbschat,

Affiliation Goethe-University Hospital, Frankfurt am Main, Germany
⨯
Haitham Mutlak,

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Pia Alexandra Ockelmann,

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Sabine Tacke,

Affiliation Department of Veterinary Clinical Sciences, Clinic for Small Animals Surgery, Justus-Liebig University, Giessen, Germany
⨯
Kai Zacharowski,

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Christin Reissig,

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
David Stay,

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Bertram Scheller

Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
⨯

Prednisolone as Preservation Additive Prevents from Ischemia Reperfusion Injury in a Rat Model of Orthotopic Lung Transplantation

Patrick Paulus,
Johannes Holfeld,
Anja Urbschat,
Haitham Mutlak,
Pia Alexandra Ockelmann,
Sabine Tacke,
Kai Zacharowski,
Christin Reissig,
David Stay,
Bertram Scheller

Published: August 29, 2013
https://doi.org/10.1371/journal.pone.0073298

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Macrophages
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Lung transplantation
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Inflammation
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