The Flavonoid Apigenin Downregulates CDK1 by Directly Targeting Ribosomal Protein S9

Open Access

Peer-reviewed

Research Article

Yosuke Iizumi,

Affiliation Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
⨯
Masakatsu Oishi,

Affiliations Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan, Department of Urology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
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Tomoyuki Taniguchi,

Affiliation Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
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Wakana Goi,

Affiliation Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
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Yoshihiro Sowa,

Affiliation Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
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Toshiyuki Sakai

* E-mail: tsakai@koto.kpu-m.ac.jp

Affiliation Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
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Transfection
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Small interfering RNA
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Cell cycle and cell division
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Immunoblotting
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Protein synthesis
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Malignant tumors
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Cyclins
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Colorectal cancer
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