CD4+ T Cells Play a Critical Role in the Generation of Primary and Memory Antitumor Immune Responses Elicited by SA-4-1BBL and TAA-Based Vaccines in Mouse Tumor Models

Open Access

Peer-reviewed

Research Article

CD4⁺ T Cells Play a Critical Role in the Generation of Primary and Memory Antitumor Immune Responses Elicited by SA-4-1BBL and TAA-Based Vaccines in Mouse Tumor Models

Rajesh K. Sharma,

Affiliation Institute for Cellular Therapeutics, Department of Microbiology and Immunology and James Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
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Esma S. Yolcu,

Affiliation Institute for Cellular Therapeutics, Department of Microbiology and Immunology and James Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
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Abhishek K. Srivastava,

Affiliation Institute for Cellular Therapeutics, Department of Microbiology and Immunology and James Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
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Haval Shirwan

* E-mail: haval.shirwan@louisville.edu

Affiliation Institute for Cellular Therapeutics, Department of Microbiology and Immunology and James Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
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T cells
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Cancers and neoplasms
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Cytotoxic T cells
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Vaccination and immunization
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Malignant tumors
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Immune response
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Vaccines
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Long term memory
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