Systemic Inflammation in Non-Demented Elderly Human Subjects: Brain Microstructure and Cognition

Konstantinos Arfanakis; Debra A. Fleischman; Giorgia Grisot; Christopher M. Barth; Anna Varentsova; Martha C. Morris; Lisa L. Barnes; David A. Bennett

doi:10.1371/journal.pone.0073107

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Open Access

Peer-reviewed

Research Article

Systemic Inflammation in Non-Demented Elderly Human Subjects: Brain Microstructure and Cognition

Konstantinos Arfanakis ,

* E-mail: arfanakis@iit.edu

Affiliations Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, United States of America, Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, Illinois, United States of America
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Debra A. Fleischman,

Affiliations Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, United States of America
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Giorgia Grisot,

Affiliation Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, United States of America
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Christopher M. Barth,

Affiliation Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, United States of America
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Anna Varentsova,

Affiliation Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, United States of America
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Martha C. Morris,

Affiliation Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America
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Lisa L. Barnes,

Affiliations Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, United States of America
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David A. Bennett

Affiliations Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America
⨯

Systemic Inflammation in Non-Demented Elderly Human Subjects: Brain Microstructure and Cognition

Konstantinos Arfanakis,
Debra A. Fleischman,
Giorgia Grisot,
Christopher M. Barth,
Anna Varentsova,
Martha C. Morris,
Lisa L. Barnes,
David A. Bennett

Published: August 26, 2013
https://doi.org/10.1371/journal.pone.0073107

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Inflammation
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Central nervous system
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Corpus callosum
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Microstructure
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Diffusion tensor imaging
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Anisotropy
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Elderly
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Magnetic resonance imaging
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