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Open Access

Peer-reviewed

Research Article

Inhibition of Oxidative Stress-Elicited AKT Activation Facilitates PPARγ Agonist-Mediated Inhibition of Stem Cell Character and Tumor Growth of Liver Cancer Cells

Lanlan Liu ,

Contributed equally to this work with: Lanlan Liu, Zhaojuan Yang

Affiliations State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Developmental and Regenerative Biology, College of Life Science and Technology, Jinan University, Guangzhou, China
⨯
Zhaojuan Yang ,

Contributed equally to this work with: Lanlan Liu, Zhaojuan Yang

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Yingqian Xu,

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Jingyi Li,

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Dongxu Xu,

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Li Zhang,

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Jiabin Sun,

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Suhua Xia,

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Feiyan Zou,

Affiliation Department of Developmental and Regenerative Biology, College of Life Science and Technology, Jinan University, Guangzhou, China
⨯
Yongzhong Liu

* E-mail: liuyzg@yahoo.com

Affiliation State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯

Inhibition of Oxidative Stress-Elicited AKT Activation Facilitates PPARγ Agonist-Mediated Inhibition of Stem Cell Character and Tumor Growth of Liver Cancer Cells

Lanlan Liu,
Zhaojuan Yang,
Yingqian Xu,
Jingyi Li,
Dongxu Xu,
Li Zhang,
Jiabin Sun,
Suhua Xia,
Feiyan Zou,
Yongzhong Liu

x

Published: August 30, 2013
https://doi.org/10.1371/journal.pone.0073038

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Hepatocellular carcinoma
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Small interfering RNA
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Stem cell therapy
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Cancers and neoplasms
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