Integrin – Dependent Mechanotransduction in Mechanically Stimulated Human Annulus Fibrosus Cells: Evidence for an Alternative Mechanotransduction Pathway Operating with Degeneration

Open Access

Peer-reviewed

Research Article

Hamish T. J. Gilbert,

Affiliation Centre for Regenerative Medicine, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, United Kingdom
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Navraj S. Nagra,

Affiliation Centre for Regenerative Medicine, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, United Kingdom
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Anthony J. Freemont,

Affiliation Centre for Regenerative Medicine, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, United Kingdom
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Sarah J. Millward-Sadler,

Affiliation Centre for Regenerative Medicine, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, United Kingdom
⨯
Judith A. Hoyland

* E-mail: Judith.Hoyland@manchester.ac.uk

Affiliation Centre for Regenerative Medicine, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, United Kingdom
⨯

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Gene expression
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Integrins
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Phosphorylation
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Collagens
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Chondrocytes
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Extracellular matrix
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Extracellular matrix proteins
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Cell physiology
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