Age of Onset of RNA Toxicity Influences Phenotypic Severity: Evidence from an Inducible Mouse Model of Myotonic Dystrophy (DM1)

Open Access

Peer-reviewed

Research Article

Jordan T. Gladman,

Affiliation Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Mahua Mandal,

Affiliation Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Varadamurthy Srinivasan,

Affiliation Parexel International, Bethesda, Maryland, United States of America
⨯
Mani S. Mahadevan

* E-mail: mahadevan@virginia.edu

Affiliation Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
⨯

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Mouse models
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Myotonic dystrophy
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Toxicity
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Skeletal muscles
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Hand strength
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Doxycycline
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RNA splicing
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Animal models of disease
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