TNF-α Induces Cytosolic Phospholipase A2 Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation

Open Access

Peer-reviewed

Research Article

TNF-α Induces Cytosolic Phospholipase A₂ Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation

I-Ta Lee ,

Contributed equally to this work with: I-Ta Lee, Chih-Chung Lin

Affiliations Department of Anesthetics, Chang Gung Memorial Hospital at Lin-Kou and College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan, Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
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Chih-Chung Lin ,

Contributed equally to this work with: I-Ta Lee, Chih-Chung Lin

Affiliation Department of Anesthetics, Chang Gung Memorial Hospital at Lin-Kou and College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
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Shin-Ei Cheng,

Affiliation Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
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Li-Der Hsiao,

Affiliation Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
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Yu-Chun Hsiao,

Affiliation Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
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Chuen-Mao Yang

* E-mail: chuenmao@mail.cgu.edu.tw

Affiliation Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
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Transcription factors
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Protein expression
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MAPK signaling cascades
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Small interfering RNA
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Transfection
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Inflammation
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Immunoprecipitation
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Mouse models
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