Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes

Jianhua Mao; Dayan Wang; Parikka Mataleena; Bing He; Dadi Niu; Kan Katayama; Xiangjun Xu; Juha RM Ojala; Wenjing Wang; Qiang Shu; Lizhong Du; Aimin Liu; Timo Pikkarainen; Jaakko Patrakka; Karl Tryggvason

doi:10.1371/journal.pone.0072750

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Open Access

Peer-reviewed

Research Article

Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes

Jianhua Mao ,

* E-mail: maojh88@gmail.com (JM); Karl.tryggvason@ki.se (KT)

Affiliation Department of Nephrology, The Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, P. R. China
⨯
Dayan Wang,

Affiliation Department of Nephrology, The Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, P. R. China
⨯
Parikka Mataleena,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Bing He,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Dadi Niu,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Kan Katayama,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Xiangjun Xu,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Juha RM Ojala,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Wenjing Wang,

Affiliation Department of Nephrology, The Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, P. R. China
⨯
Qiang Shu,

Affiliation Department of Nephrology, The Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, P. R. China
⨯
Lizhong Du,

Affiliation Department of Nephrology, The Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, P. R. China
⨯
Aimin Liu,

Affiliation Department of Nephrology, The Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, P. R. China
⨯
Timo Pikkarainen,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Jaakko Patrakka,

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯
Karl Tryggvason

* E-mail: maojh88@gmail.com (JM); Karl.tryggvason@ki.se (KT)

Affiliation Division of Matrix Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
⨯

Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes

Jianhua Mao,
Dayan Wang,
Parikka Mataleena,
Bing He,
Dadi Niu,
Kan Katayama,
Xiangjun Xu,
Juha RM Ojala,
Wenjing Wang,
Qiang Shu

Published: August 19, 2013
https://doi.org/10.1371/journal.pone.0072750

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