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Open Access

Peer-reviewed

Research Article

PI3K p110γ Deletion Attenuates Murine Atherosclerosis by Reducing Macrophage Proliferation but Not Polarization or Apoptosis in Lesions

Teresa M. Zotes ,

Contributed equally to this work with: Teresa M. Zotes, Cristina F. Arias

Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain
⨯
Cristina F. Arias ,

Contributed equally to this work with: Teresa M. Zotes, Cristina F. Arias

Current address: Langone Medical Center, New York University, New York, New York, United States of America

Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain
⨯
José J. Fuster,

Current address: Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America

Affiliation Department of Epidemiology, Atherothrombosis and Imaging, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
⨯
Roberto Spada,

Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain
⨯
Sonia Pérez-Yagüe,

Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain
⨯
Emilio Hirsch,

Affiliation Department of Genetics, Biology and Biochemistry, Center for Molecular Biotechnology-University of Torino, Torino, Italy
⨯
Matthias Wymann,

Affiliation Department of Clinical and Biological Sciences, Institute of Biochemistry and Genetics- University of Basel, Basel, Switzerland
⨯
Ana C. Carrera,

Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain
⨯
Vicente Andrés,

Affiliation Department of Epidemiology, Atherothrombosis and Imaging, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
⨯
Domingo F. Barber

* E-mail: dfbarber@cnb.csic.es

Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain
⨯

PI3K p110γ Deletion Attenuates Murine Atherosclerosis by Reducing Macrophage Proliferation but Not Polarization or Apoptosis in Lesions

Teresa M. Zotes,
Cristina F. Arias,
José J. Fuster,
Roberto Spada,
Sonia Pérez-Yagüe,
Emilio Hirsch,
Matthias Wymann,
Ana C. Carrera,
Vicente Andrés,
Domingo F. Barber

x

Published: August 22, 2013
https://doi.org/10.1371/journal.pone.0072674

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Atherosclerosis
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T cells
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Cell staining
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Cell differentiation
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Immunofluorescence staining
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