Congenital Heart Block Maternal Sera Autoantibodies Target an Extracellular Epitope on the α_1G T-Type Calcium Channel in Human Fetal Hearts

• Linn S. Strandberg ,

  Contributed equally to this work with: Linn S. Strandberg, Xuezhi Cui

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Xuezhi Cui ,

  Contributed equally to this work with: Linn S. Strandberg, Xuezhi Cui

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Arianna Rath,

  Affiliation Division of Molecular Structure and Function, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Jie Liu,

  Affiliation Departments of Physiology and Medicine, University of Toronto, Toronto, Ontario, Canada

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• Earl D. Silverman,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Xiaoru Liu,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Vinayakumar Siragam,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Cameron Ackerley,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Brenda Bin Su,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Jane Yuqing Yan,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Marco Capecchi,

  Affiliation Scuola Superiore Sant'Anna, Pisa, Italy

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• Luca Biavati,

  Affiliation Scuola Superiore Sant'Anna, Pisa, Italy

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• Alice Accorroni,

  Affiliation Scuola Superiore Sant'Anna, Pisa, Italy

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• William Yuen,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Filippo Quattrone,

  Affiliation Scuola Superiore Sant'Anna, Pisa, Italy

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• Kalvin Lung,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Edgar T. Jaeggi,

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Peter H. Backx,

  Affiliations Departments of Physiology and Medicine, University of Toronto, Toronto, Ontario, Canada, Division of Cardiology, University Health Network, Toronto, Ontario, Canada

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• Charles M. Deber,

  Affiliations Division of Molecular Structure and Function, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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•  [ ... ],
• Robert M. Hamilton

  * E-mail: Robert.hamilton@sickkids.ca

  Affiliation Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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