Competence in Streptococcus pneumoniae Is a Response to an Increasing Mutational Burden

Alyssa L. Gagne; Kathleen E. Stevens; Marco Cassone; Amit Pujari; Olufunke E. Abiola; Diana J. Chang; Michael E. Sebert

doi:10.1371/journal.pone.0072613

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Peer-reviewed

Research Article

Competence in Streptococcus pneumoniae Is a Response to an Increasing Mutational Burden

Alyssa L. Gagne,

Affiliation Division of Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Kathleen E. Stevens,

Current address: Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Affiliation Division of Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Marco Cassone,

Affiliation Division of Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Amit Pujari,

Affiliation School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Olufunke E. Abiola,

Current address: Shire Human Genetic Therapies (HGT), Lexington, Massachusetts, United States of America

Affiliation School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Diana J. Chang,

Current address: University of California Davis School of Medicine, Sacramento, California, United States of America

Affiliation School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Michael E. Sebert

* E-mail: sebert@email.chop.edu

Affiliations Division of Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Competence in Streptococcus pneumoniae Is a Response to an Increasing Mutational Burden

Alyssa L. Gagne,
Kathleen E. Stevens,
Marco Cassone,
Amit Pujari,
Olufunke E. Abiola,
Diana J. Chang,
Michael E. Sebert

Published: August 13, 2013
https://doi.org/10.1371/journal.pone.0072613

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Genomics
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Mutation
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Single nucleotide polymorphisms
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Deletion mutation
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DNA repair
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