Pseudomonas aeruginosa Pyocyanin Activates NRF2-ARE-Mediated Transcriptional Response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP Kinase Signaling in Pulmonary Epithelial Cells

Open Access

Peer-reviewed

Research Article

Ying Xu ,

Contributed equally to this work with: Ying Xu, Chaohui Duan

Affiliations Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, Laboratory of Clinical Immunology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China
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Chaohui Duan ,

Contributed equally to this work with: Ying Xu, Chaohui Duan

Affiliation Laboratory of Clinical Immunology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China
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Zhizhou Kuang,

Affiliation Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Yonghua Hao,

Affiliation Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Jayme L. Jeffries,

Affiliation Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Gee W. Lau

* E-mail: geelau@illinois.edu

Affiliation Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Epithelial cells
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Antioxidants
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Cytoplasm
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DNA transcription
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EGFR signaling
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Densitometry
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Oxidative stress
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Signal inhibition
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