Insulin-Producing Cells Derived from Human Embryonic Stem Cells: Comparison of Definitive Endoderm- and Nestin-Positive Progenitor-Based Differentiation Strategies

Rui Wei; Jin Yang; Wenfang Hou; Guoqiang Liu; Meijuan Gao; Lin Zhang; Haining Wang; Genhong Mao; Hongwei Gao; Guian Chen; Tianpei Hong

doi:10.1371/journal.pone.0072513

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Peer-reviewed

Research Article

Insulin-Producing Cells Derived from Human Embryonic Stem Cells: Comparison of Definitive Endoderm- and Nestin-Positive Progenitor-Based Differentiation Strategies

Rui Wei,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Jin Yang,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Wenfang Hou,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Guoqiang Liu,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Meijuan Gao,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Lin Zhang,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Haining Wang,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Genhong Mao,

Affiliations Reproductive Medical Center, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Hongwei Gao,

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Guian Chen,

Affiliations Reproductive Medical Center, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯
Tianpei Hong

* E-mail: tpho66@bjmu.edu.cn

Affiliations Department of Endocrinology and Metabolism, Peking University Third Hospital, Haidian District, Beijing, China, Clinical Stem Cell Research Center, Peking University Third Hospital, Haidian District, Beijing, China
⨯

Insulin-Producing Cells Derived from Human Embryonic Stem Cells: Comparison of Definitive Endoderm- and Nestin-Positive Progenitor-Based Differentiation Strategies

Rui Wei,
Jin Yang,
Wenfang Hou,
Guoqiang Liu,
Meijuan Gao,
Lin Zhang,
Haining Wang,
Genhong Mao,
Hongwei Gao,
Guian Chen

Published: August 12, 2013
https://doi.org/10.1371/journal.pone.0072513

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