Acetylation of Drosha on the N-Terminus Inhibits Its Degradation by Ubiquitination

Xiaoli Tang; Sicheng Wen; Dong Zheng; Lynne Tucker; Lulu Cao; Dennis Pantazatos; Steven F. Moss; Bharat Ramratnam

doi:10.1371/journal.pone.0072503

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Open Access

Peer-reviewed

Research Article

Acetylation of Drosha on the N-Terminus Inhibits Its Degradation by Ubiquitination

Xiaoli Tang,

Affiliation Laboratory of Retrovirology, Division of Infectious Diseases, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Sicheng Wen,

Affiliation Division of Gastroenterology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Dong Zheng,

Affiliation Laboratory of Retrovirology, Division of Infectious Diseases, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Lynne Tucker,

Affiliation Laboratory of Retrovirology, Division of Infectious Diseases, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Lulu Cao,

Affiliation COBRE Center for Cancer Research, Division of Hematology and Oncology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Dennis Pantazatos,

Affiliation COBRE Center for Cancer Research, Division of Hematology and Oncology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Steven F. Moss,

Affiliation Division of Gastroenterology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Bharat Ramratnam

* E-mail: BRamratnam@Lifespan.org

Affiliations Laboratory of Retrovirology, Division of Infectious Diseases, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America, COBRE Center for Cancer Research, Division of Hematology and Oncology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯

Acetylation of Drosha on the N-Terminus Inhibits Its Degradation by Ubiquitination

Xiaoli Tang,
Sicheng Wen,
Dong Zheng,
Lynne Tucker,
Lulu Cao,
Dennis Pantazatos,
Steven F. Moss,
Bharat Ramratnam

Published: August 29, 2013
https://doi.org/10.1371/journal.pone.0072503

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Acetylation
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Lysine
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MicroRNAs
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Helicobacter pylori
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Immunoprecipitation
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Transfection
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Ubiquitination
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Messenger RNA
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