Improvement of a Predictive Model of Castration-Resistant Prostate Cancer: Functional Genetic Variants in TGFβ1 Signaling Pathway Modulation

Ana L. Teixeira; Mónica Gomes; Augusto Nogueira; Andreia S. Azevedo; Joana Assis; Francisca Dias; Juliana I. Santos; Francisco Lobo; António Morais; Joaquina Maurício; Rui Medeiros

doi:10.1371/journal.pone.0072419

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Open Access

Peer-reviewed

Research Article

Improvement of a Predictive Model of Castration-Resistant Prostate Cancer: Functional Genetic Variants in TGFβ1 Signaling Pathway Modulation

Ana L. Teixeira,

Affiliations Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences - University of Porto, Porto, Portugal
⨯
Mónica Gomes,

Affiliations Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences - University of Porto, Porto, Portugal
⨯
Augusto Nogueira,

Affiliation Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal
⨯
Andreia S. Azevedo,

Affiliation Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal
⨯
Joana Assis,

Affiliation Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal
⨯
Francisca Dias,

Affiliations Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences - University of Porto, Porto, Portugal
⨯
Juliana I. Santos,

Affiliations Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences - University of Porto, Porto, Portugal
⨯
Francisco Lobo,

Affiliation Urology Department, Portuguese Institute of Oncology - Porto, Porto, Portugal
⨯
António Morais,

Affiliation Urology Department, Portuguese Institute of Oncology - Porto, Porto, Portugal
⨯
Joaquina Maurício,

Affiliation Oncology Department, Portuguese Institute of Oncology - Porto, Porto, Portugal
⨯
Rui Medeiros

* E-mail: ruimedei@ipoporto.min-saude.pt

Affiliations Molecular Oncology Group, Portuguese Institute of Oncology - Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences - University of Porto, Porto, Portugal, Faculty of Health Sciences of Fernando Pessoa University, Porto, Portugal, Research Department, Portuguese League Against Cancer (NRNorte), Porto, Portugal
⨯

Improvement of a Predictive Model of Castration-Resistant Prostate Cancer: Functional Genetic Variants in TGFβ1 Signaling Pathway Modulation

Ana L. Teixeira,
Mónica Gomes,
Augusto Nogueira,
Andreia S. Azevedo,
Joana Assis,
Francisca Dias,
Juliana I. Santos,
Francisco Lobo,
António Morais,
Joaquina Maurício

Published: August 9, 2013
https://doi.org/10.1371/journal.pone.0072419

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Prostate cancer
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TGF-beta signaling cascade
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Breast cancer
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Cancer detection and diagnosis
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Gastric cancer
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Cancer risk factors
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Colorectal cancer
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Gene expression
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