Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury

Terry Yin; Timothy E. Lindley; Gregory W. Albert; Raheel Ahmed; Peter B. Schmeiser; M. Sean Grady; Matthew A. Howard; Michael J. Welsh

doi:10.1371/journal.pone.0072379

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Peer-reviewed

Research Article

Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury

Terry Yin,

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
Timothy E. Lindley,

Affiliation Department of Neurosurgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
Gregory W. Albert,

Affiliation Department of Neurosurgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
Raheel Ahmed,

Affiliation Department of Neurosurgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
Peter B. Schmeiser,

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
M. Sean Grady,

Affiliation Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Matthew A. Howard,

Affiliation Department of Neurosurgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
Michael J. Welsh

* E-mail: michael-welsh@uiowa.edu

Affiliations Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Neurosurgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Howard Hughes Medical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯

Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury

Terry Yin,
Timothy E. Lindley,
Gregory W. Albert,
Raheel Ahmed,
Peter B. Schmeiser,
M. Sean Grady,
Matthew A. Howard,
Michael J. Welsh

Published: August 26, 2013
https://doi.org/10.1371/journal.pone.0072379

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