Absence of Functional Leptin Receptor Isoforms in the POUND (Leprdb/lb) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation

Phonepasong Arounleut; Matthew Bowser; Sunil Upadhyay; Xing-Ming Shi; Sadanand Fulzele; Maribeth H. Johnson; Alexis M. Stranahan; William D. Hill; Carlos M. Isales; Mark W. Hamrick

doi:10.1371/journal.pone.0072330

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Peer-reviewed

Research Article

Absence of Functional Leptin Receptor Isoforms in the POUND (Lepr^db/lb) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation

Phonepasong Arounleut,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Matthew Bowser,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Sunil Upadhyay,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Xing-Ming Shi,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Sadanand Fulzele,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Maribeth H. Johnson,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Alexis M. Stranahan,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
William D. Hill,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Carlos M. Isales,

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯
Mark W. Hamrick

* E-mail: mhamrick@gru.edu

Affiliation Georgia Regents University (formerly Georgia Health Sciences University), Augusta, Georgia, United States of America
⨯

Absence of Functional Leptin Receptor Isoforms in the POUND (Lepr^db/lb) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation

Phonepasong Arounleut,
Matthew Bowser,
Sunil Upadhyay,
Xing-Ming Shi,
Sadanand Fulzele,
Maribeth H. Johnson,
Alexis M. Stranahan,
William D. Hill,
Carlos M. Isales,
Mark W. Hamrick

Published: August 14, 2013
https://doi.org/10.1371/journal.pone.0072330

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Leptin
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Myoblasts
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Skeletal muscles
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Mouse models
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Muscle differentiation
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Muscle proteins
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Enzyme-linked immunoassays
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Muscle fibers
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