Exome Sequencing and Functional Analysis Identifies a Novel Mutation in EXT1 Gene That Causes Multiple Osteochondromas

Feng Zhang; Jinlong Liang; Xiong Guo; Yingang Zhang; Yan Wen; Qiang Li; Zengtie Zhang; Weijuan Ma; Lanlan Dai; Xuanzhu Liu; Ling Yang; Jun Wang

doi:10.1371/journal.pone.0072316

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Open Access

Peer-reviewed

Research Article

Exome Sequencing and Functional Analysis Identifies a Novel Mutation in EXT1 Gene That Causes Multiple Osteochondromas

Feng Zhang ,

Contributed equally to this work with: Feng Zhang, Jinlong Liang

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China
⨯
Jinlong Liang ,

Contributed equally to this work with: Feng Zhang, Jinlong Liang

Affiliation BGI-Shenzhen, Shenzhen, China
⨯
Xiong Guo ,

* E-mail: guox@mail.xjtu.edu.cn (XG); wangjun30@gmail.com (JW)

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China
⨯
Yingang Zhang,

Affiliation Department of Orthopedics, First Affiliated Hospital of Medical College of Xi’an Jiaotong University, Xi’an, Shaanxi, China
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Yan Wen,

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China
⨯
Qiang Li,

Affiliation Department of Orthopedics, First People’s Hospital of Longxi County, Gansu, China
⨯
Zengtie Zhang,

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China
⨯
Weijuan Ma,

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China
⨯
Lanlan Dai,

Affiliation BGI-Shenzhen, Shenzhen, China
⨯
Xuanzhu Liu,

Affiliation BGI-Shenzhen, Shenzhen, China
⨯
Ling Yang,

Affiliation BGI-Tianjin, Tianjin, China
⨯
Jun Wang

* E-mail: guox@mail.xjtu.edu.cn (XG); wangjun30@gmail.com (JW)

Affiliations BGI-Shenzhen, Shenzhen, China, Department of Biology, University of Copenhagen, Copenhagen, Denmark, King Abdulaziz University, Jeddah, Saudi Arabia
⨯

Exome Sequencing and Functional Analysis Identifies a Novel Mutation in EXT1 Gene That Causes Multiple Osteochondromas

Feng Zhang,
Jinlong Liang,
Xiong Guo,
Yingang Zhang,
Yan Wen,
Qiang Li,
Zengtie Zhang,
Weijuan Ma,
Lanlan Dai,
Xuanzhu Liu

Published: August 29, 2013
https://doi.org/10.1371/journal.pone.0072316

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