Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE

Ramzi Khattar; Olga Luft; Nataliya Yavorska; Itay Shalev; M. James Phillips; Oyedele Adeyi; Darrin Gao; Agata Bartczak; Peter Urbanellis; Wendy Shyu; Jianhua Zhang; Justin Manuel; Gary A. Levy; Nazia Selzner

doi:10.1371/journal.pone.0072309

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Open Access

Peer-reviewed

Research Article

Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE

Ramzi Khattar,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Olga Luft,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Nataliya Yavorska,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Itay Shalev,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
M. James Phillips,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Oyedele Adeyi,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Darrin Gao,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Agata Bartczak,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Peter Urbanellis,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Wendy Shyu,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Jianhua Zhang,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Justin Manuel,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Gary A. Levy,

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯
Nazia Selzner

* E-mail: nazia.selzner@uhn.ca

Affiliation University of Toronto Transplantation Institute, University of Toronto, Toronto, Ontario, Canada
⨯

Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE

Ramzi Khattar,
Olga Luft,
Nataliya Yavorska,
Itay Shalev,
M. James Phillips,
Oyedele Adeyi,
Darrin Gao,
Agata Bartczak,
Peter Urbanellis,
Wendy Shyu

Published: October 11, 2013
https://doi.org/10.1371/journal.pone.0072309

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