Modulation of Ocular Surface Glycocalyx Barrier Function by a Galectin-3 N-terminal Deletion Mutant and Membrane-Anchored Synthetic Glycopolymers

Jerome Mauris; Flavio Mantelli; Ashley M. Woodward; Ziyhi Cao; Carolyn R. Bertozzi; Noorjahan Panjwani; Kamil Godula; Pablo Argüeso

doi:10.1371/journal.pone.0072304

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Peer-reviewed

Research Article

Modulation of Ocular Surface Glycocalyx Barrier Function by a Galectin-3 N-terminal Deletion Mutant and Membrane-Anchored Synthetic Glycopolymers

Jerome Mauris,

Affiliation Schepens Eye Research Institute and Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Flavio Mantelli,

Current address: IRCCS G.B. Bietti Eye Foundation, Rome, Italy

Affiliation Schepens Eye Research Institute and Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ashley M. Woodward,

Affiliation Schepens Eye Research Institute and Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Ziyhi Cao,

Affiliation Department of Ophthalmology, Center for Vision Research, Tufts University Medical School, Boston, Massachusetts, United States of America
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Carolyn R. Bertozzi,

Affiliations Departments of Chemistry, Molecular and Cell Biology and Howard Hughes Medical Institute, University of California, United States of America, Materials Sciences Division and The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Noorjahan Panjwani,

Affiliation Department of Ophthalmology, Center for Vision Research, Tufts University Medical School, Boston, Massachusetts, United States of America
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Kamil Godula,

Current address: Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, United States of America

Affiliation Materials Sciences Division and The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Pablo Argüeso

* E-mail: pablo_argueso@meei.harvard.edu

Affiliation Schepens Eye Research Institute and Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Modulation of Ocular Surface Glycocalyx Barrier Function by a Galectin-3 N-terminal Deletion Mutant and Membrane-Anchored Synthetic Glycopolymers

Jerome Mauris,
Flavio Mantelli,
Ashley M. Woodward,
Ziyhi Cao,
Carolyn R. Bertozzi,
Noorjahan Panjwani,
Kamil Godula,
Pablo Argüeso

Published: August 19, 2013
https://doi.org/10.1371/journal.pone.0072304

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