Both PAX4 and MAFA Are Expressed in a Substantial Proportion of Normal Human Pancreatic Alpha Cells and Deregulated in Patients with Type 2 Diabetes

• Rémy Bonnavion ,

  Contributed equally to this work with: Rémy Bonnavion, Rami Jaafar

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France

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• Rami Jaafar ,

  Contributed equally to this work with: Rémy Bonnavion, Rami Jaafar

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France

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• Julie Kerr-Conte,

  Affiliation Université Lille Nord de France/INSERM U859 Biotherapies of Diabetes, Faculty of Medicine, Lille, France

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• Fouzia Assade,

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France

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• Esther van Stralen,

  Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences & University Medical Centre Utrecht, Utrecht, The Netherlands

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• Emmanuelle Leteurtre,

  Affiliation Department of Pathology, Centre Hospitalier Régional et Universitaire de Lille, Lille, France

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• Célio Pouponnot,

  Affiliation Institut Curie, CNRS UMR3347, INSERM U1021, Orsay, France

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• Sofia Gargani,

  Affiliation Université Lille Nord de France/INSERM U859 Biotherapies of Diabetes, Faculty of Medicine, Lille, France

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• François Pattou,

  Affiliation Université Lille Nord de France/INSERM U859 Biotherapies of Diabetes, Faculty of Medicine, Lille, France

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• Philippe Bertolino,

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France

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• Martine Cordier-Bussat,

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France

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• Jieli Lu ,

  * E-mail: ljl11319@rjh.com.cn (JLL); chang.zhang@lyon.unicancer.fr (CXZ)

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France, The E-Institute of Shanghai, Sino-French Life Science and Genomic Center, Ruijin Hospital, Shanghai, China, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao-Tong University, Shanghai, China

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• Chang Xian Zhang

  * E-mail: ljl11319@rjh.com.cn (JLL); chang.zhang@lyon.unicancer.fr (CXZ)

  Affiliations Inserm U1052, Lyon, France, CNRS UMR5286, Lyon, France, Université de Lyon, Lyon, France, The E-Institute of Shanghai, Sino-French Life Science and Genomic Center, Ruijin Hospital, Shanghai, China

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