The Soluble Guanylate Cyclase Activator BAY 58-2667 Protects against Morbidity and Mortality in Endotoxic Shock by Recoupling Organ Systems

• Benjamin Vandendriessche,

  Affiliations Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

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• Elke Rogge,

  Affiliations Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

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• Vera Goossens,

  Affiliations Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

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• Peter Vandenabeele,

  Affiliations Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

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• Johannes-Peter Stasch,

  Affiliation Institute of Cardiovascular Research, Bayer HealthCare, Wuppertal, Germany

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• Peter Brouckaert ,

  ¶These authors are joint senior authors on this work.

  Affiliations Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

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• Anje Cauwels

  * E-mail: anje.cauwels@dmbr.ugent.be

  ¶These authors are joint senior authors on this work.

  Affiliations Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

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