Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts

Open Access

Peer-reviewed

Research Article

Parvathi Chary,

Affiliation Center for Research on Occupational and Environmental Toxicology, Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America
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William A. Beard,

Affiliation Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, North Carolina, United States of America
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Samuel H. Wilson,

Affiliation Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, North Carolina, United States of America
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R. Stephen Lloyd

* E-mail: lloydst@ohsu.edu

Affiliation Center for Research on Occupational and Environmental Toxicology, Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America
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HIV-1
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Polymerases
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Nucleotides
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DNA synthesis
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DNA polymerase
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DNA replication
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DNA structure
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Primer extension
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