Us3 Kinase Encoded by Herpes Simplex Virus 1 Mediates Downregulation of Cell Surface Major Histocompatibility Complex Class I and Evasion of CD8⁺ T Cells

• Takahiko Imai,

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Nippon Institute for Biological Science, Ome, Tokyo, Japan

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• Naoto Koyanagi,

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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• Ryo Ogawa,

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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• Keiko Shindo,

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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• Tadahiro Suenaga,

  Affiliations Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, World Premier International Research Center Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan

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• Ayuko Sato,

  Affiliation Division of Mucosal Immunology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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• Jun Arii,

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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• Akihisa Kato,

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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• Hiroshi Kiyono,

  Affiliations Division of Mucosal Immunology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Hisashi Arase,

  Affiliations Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan, Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, World Premier International Research Center Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan

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• Yasushi Kawaguchi

  * E-mail: ykawagu@ims.u-tokyo.ac.jp

  Affiliations Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan, Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan

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