Effects of Androgen Deprivation on Cerebral Morphometry in Prostate Cancer Patients – An Exploratory Study

Herta H. Chao; Sien Hu; Jaime S. Ide; Edward Uchio; Sheng Zhang; Michal Rose; John Concato; Chiang-shan R. Li

doi:10.1371/journal.pone.0072032

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Open Access

Peer-reviewed

Research Article

Effects of Androgen Deprivation on Cerebral Morphometry in Prostate Cancer Patients – An Exploratory Study

Herta H. Chao ,

* E-mail: herta.chao@yale.edu

Affiliations Department of Internal Medicine & Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Medical Service, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America
⨯
Sien Hu,

Affiliation Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America
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Jaime S. Ide,

Affiliation Department of Science and Technology, Federal University of Sao Paolo, Salo Paolo, Brazil
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Edward Uchio,

Affiliation Tower Research, Los Angeles, California, United States of America
⨯
Sheng Zhang,

Affiliation Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Michal Rose,

Affiliations Department of Internal Medicine & Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Medical Service, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America
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John Concato,

Affiliations Department of Internal Medicine & Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Medical Service, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America, Clinical Epidemiology Research Center, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America
⨯
Chiang-shan R. Li

Affiliations Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America, Deparment of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut, United States of America
⨯

Effects of Androgen Deprivation on Cerebral Morphometry in Prostate Cancer Patients – An Exploratory Study

Herta H. Chao,
Sien Hu,
Jaime S. Ide,
Edward Uchio,
Sheng Zhang,
Michal Rose,
John Concato,
Chiang-shan R. Li

Published: August 19, 2013
https://doi.org/10.1371/journal.pone.0072032

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Central nervous system
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Prostate cancer
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Cancer treatment
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Working memory
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Androgens
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Neuroimaging
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Reaction time
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Voxel-based morphometry
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