M1 Muscarinic Receptor Activation Mediates Cell Death in M1-HEK293 Cells

E. Scott Graham; Kerhan K. Woo; Miranda Aalderink; Sandie Fry; Jeffrey M. Greenwood; Michelle Glass; Mike Dragunow

doi:10.1371/journal.pone.0072011

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Peer-reviewed

Research Article

M1 Muscarinic Receptor Activation Mediates Cell Death in M1-HEK293 Cells

E. Scott Graham,

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯
Kerhan K. Woo,

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯
Miranda Aalderink,

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯
Sandie Fry,

Current address: Thermo Fisher Scientific, Albany, Auckland, New Zealand

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯
Jeffrey M. Greenwood,

Current address: The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯
Michelle Glass,

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯
Mike Dragunow

* E-mail: m.dragunow@auckland.ac.nz

Affiliation Department of Pharmacology and Clinical Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
⨯

M1 Muscarinic Receptor Activation Mediates Cell Death in M1-HEK293 Cells

E. Scott Graham,
Kerhan K. Woo,
Miranda Aalderink,
Sandie Fry,
Jeffrey M. Greenwood,
Michelle Glass,
Mike Dragunow

Published: September 2, 2013
https://doi.org/10.1371/journal.pone.0072011

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Carbachol
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Muscarinic acetylcholine receptors
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Cell death
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Apoptosis
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Transfection
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Cell staining
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HEK 293 cells
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