Genetic Inactivation of Pyruvate Dehydrogenase Kinases Improves Hepatic Insulin Resistance Induced Diabetes

Open Access

Peer-reviewed

Research Article

Rongya Tao,

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Xiwen Xiong,

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Robert A. Harris,

Affiliations Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Richard Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, United States of America
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Morris F. White,

Affiliation Division of Endocrinology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Xiaocheng C. Dong

* E-mail: xcdong@iu.edu

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Genetically modified animals
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Insulin
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Mouse models
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Diabetes mellitus
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Insulin resistance
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Gene expression
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Glucose tolerance
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Blood sugar
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