Distinct Phenotypic Differences Associated with Differential Amplification of Receptor Tyrosine Kinase Genes at 4q12 in Glioblastoma

Open Access

Peer-reviewed

Research Article

Anna Burford,

Affiliations Divisions of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom, Cancer Therapeutics, The Institute of Cancer Research, Sutton, United Kingdom
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Suzanne E. Little,

Affiliations Divisions of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom, Cancer Therapeutics, The Institute of Cancer Research, Sutton, United Kingdom
⨯
Alexa Jury,

Affiliations Divisions of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom, Cancer Therapeutics, The Institute of Cancer Research, Sutton, United Kingdom
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Sergey Popov,

Affiliations Divisions of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom, Cancer Therapeutics, The Institute of Cancer Research, Sutton, United Kingdom
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Ross Laxton,

Affiliation Neuropathology, King's College Hospital, London, United Kingdom
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Lawrence Doey,

Affiliation Neuropathology, King's College Hospital, London, United Kingdom
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Safa Al-Sarraj,

Affiliation Neuropathology, King's College Hospital, London, United Kingdom
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Juliane M. Jürgensmeier,

Affiliation AstraZeneca, Alderley Park, Macclesfield, United Kingdom
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Chris Jones

* E-mail: chris.jones@icr.ac.uk

Affiliations Divisions of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom, Cancer Therapeutics, The Institute of Cancer Research, Sutton, United Kingdom
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Glioblastoma multiforme
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Cancers and neoplasms
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Methylation
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Signal amplification
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DNA methylation
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Oligodendroglioma
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Astrocytoma
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Endothelial cells
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