Mangiferin Prevents Guinea Pig Tracheal Contraction via Activation of the Nitric Oxide-Cyclic GMP Pathway

Open Access

Peer-reviewed

Research Article

Aline B. Vieira,

Affiliation Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
⨯
Luciana P. Coelho,

Affiliation Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
⨯
Daniella B. R. Insuela,

Affiliation Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
⨯
Vinicius F. Carvalho,

Affiliation Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
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Marcelo H. dos Santos,

Affiliation Laboratory of Phytochemistry and Medicinal and Chemistry, Department of Pharmacy, Alfenas, Federal University of Alfenas, MG, Brazil
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Patricia MR. Silva,

Affiliation Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
⨯
Marco A. Martins

* E-mail: mmartins@ioc.fiocruz.br

Affiliation Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil
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Carbachol
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Nitric oxide
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Potassium channels
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Guinea pigs
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Smooth muscles
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Trachea
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Histamine
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Muscle contraction
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