Ex-Vivo Dynamic 3-D Culture of Human Tissues in the RCCS™ Bioreactor Allows the Study of Multiple Myeloma Biology and Response to Therapy

• Marina Ferrarini ,

  Contributed equally to this work with: Marina Ferrarini, Nathalie Steimberg

  * E-mail: ferrarini.marina@hsr.it (MF); ferrero.elisabetta@hsr.it (EF)

  Affiliation Department of Oncology, San Raffaele Scientific Institute, Milan, Italy

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• Nathalie Steimberg ,

  Contributed equally to this work with: Marina Ferrarini, Nathalie Steimberg

  Affiliation Laboratory of Tissue Engineering, Department of Clinical and Experimental Sciences, School of Medicine, University of Brescia, Brescia, Italy

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• Maurilio Ponzoni,

  Affiliation Pathology Unit, San Raffaele Scientific Institute, Milan, Italy

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• Daniela Belloni,

  Affiliation Department of Oncology, San Raffaele Scientific Institute, Milan, Italy

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• Angiola Berenzi,

  Affiliation Institute of Pathological Anatomy, Department of Clinical and Experimental Sciences, School of Medicine, University of Brescia, Brescia, Italy

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• Stefania Girlanda,

  Affiliation Bone Marrow Transplantation Unit, San Raffaele Scientific Institute, Milan, Italy

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• Federico Caligaris-Cappio,

  Affiliations Department of Oncology, San Raffaele Scientific Institute, Milan, Italy, Vita-Salute San Raffaele University School of Medicine, Milan, Italy

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• Giovanna Mazzoleni ,

  ¶These authors also contributed equally to this work.

  Affiliation Laboratory of Tissue Engineering, Department of Clinical and Experimental Sciences, School of Medicine, University of Brescia, Brescia, Italy

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• Elisabetta Ferrero

  * E-mail: ferrarini.marina@hsr.it (MF); ferrero.elisabetta@hsr.it (EF)

  ¶These authors also contributed equally to this work.

  Affiliation Department of Oncology, San Raffaele Scientific Institute, Milan, Italy

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