Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector

Satoshi Horino; Toru Uchiyama; Takanori So; Hiroyuki Nagashima; Shu-lan Sun; Miki Sato; Atsuko Asao; Yoichi Haji; Yoji Sasahara; Fabio Candotti; Shigeru Tsuchiya; Shigeo Kure; Kazuo Sugamura; Naoto Ishii

doi:10.1371/journal.pone.0071594

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Open Access

Peer-reviewed

Research Article

Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector

Satoshi Horino,

Affiliations Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan, Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Toru Uchiyama,

Affiliation Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Takanori So,

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Hiroyuki Nagashima,

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Shu-lan Sun,

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Miki Sato,

Affiliation Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Atsuko Asao,

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Yoichi Haji,

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Yoji Sasahara,

Affiliation Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Fabio Candotti,

Affiliation Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Shigeru Tsuchiya,

Affiliation Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Shigeo Kure,

Affiliation Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Kazuo Sugamura,

Affiliation Miyagi Cancer Center, Natori, Japan
⨯
Naoto Ishii

* E-mail: ishiin@med.tohoku.ac.jp

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯

Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector

Satoshi Horino,
Toru Uchiyama,
Takanori So,
Hiroyuki Nagashima,
Shu-lan Sun,
Miki Sato,
Atsuko Asao,
Yoichi Haji,
Yoji Sasahara,
Fabio Candotti

Published: August 21, 2013
https://doi.org/10.1371/journal.pone.0071594

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